It is produced from a culture of the Hall strain of Clostridium botulinum and is purified by a series of acid precipitations to a crystalline complex containing the toxin and other proteins.
Botoxis a protein made from botulinum toxin, which is produced by the bacteria Clostridium botulinum. It's the same toxin that causes botulism, a serious illness that affects the nerves. In large quantities, this toxin can cause botulism, a disease that affects the nerves.
Botox has been used since the 1970s in the field of ophthalmology, and in the last 20 years, its use has expanded to several areas of health, especially dermatology. Botulinum toxin (BoNT), often abbreviated as Botox, is a neurotoxic protein produced by the bacteria Clostridium botulinum and related species. It prevents the release of the neurotransmitter acetylcholine from the axonal endings at the neuromuscular junction, thus causing flaccid paralysis. The drug is injected into specific muscles to reduce wrinkles and fine lines.
It works by blocking nerve signals to the injected muscles, which temporarily relaxes them and reduces wrinkles. Health professionals also use Botox to treat a variety of medical conditions, most of which affect the neuromuscular system. Thus, Botox Cosmetic (OnabotulinumtoxinA) was born and created a new category (and phenomenon) in the field of facial aesthetics. By preventing nerves from sending signals to the muscle to contract, Botox essentially paralyzes muscles for short periods of time.
The most common complications are ecchymosis and purpura, which could be minimized by compressing ice at injection sites before and after the botox injection. When considering Botox for any reason, it is essential to ensure that the provider is a qualified professional with the right training. According to the American Board of Cosmetic Surgery, Botox injections are the most popular cosmetic procedure nationwide. People should avoid using Botox while pregnant or breastfeeding, or if they have ever had an allergic reaction to the medication or any of its ingredients.
Contraindications for use are quite similar to those of botox, such as hypersensitivity to the components of fillers, bleeding disorders, a history of anaphylaxis because hyaluronic acid products are made from bacterial fermentation, and a history of allergies in gram-positive bacteria.